Self-driven web technologist and cross-platform solutions enthusiast with strong analytic mind. Interest in pattern recognition and integration between web platforms and databases. PhD and Engineering degrees in fields of chemistry / bioinformatics with a strong publication record in peer-reviewed journals. Java, Python & PHP programmer. Keen on rock music and rock climbing
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Implementation and development of ATLAS Beowulf type cluster network for nano-Electronic Design Automation in ToK4nEDA project
Beowulf Cluster widely-used term meaning independent computers combined into a unified system through software and networking based on commodity hardware, on a private system network. One of the main goals of ToK4nEDA project is Design of the advanced PC cluster of Beowulf type named ATLAS (Advanced Technology Laboratory Server) and its integration with local and European Grid Network (EUROGRID) for solving of large system of linear equations by direct (sparse matrices solvers) and iterative methods. The infrastructure will support industry and also other research and training projects related to ToK4nEDA such as Chameleon, Artic, Comson and EST.
Fold recognition is a method of fold detecting and protein tertiary structure prediction
applied for proteins lacking homologues sequences of known fold and structure
deposited in the Protein Data Bank. They are based on assumption that there is strictly
limited number of different protein folds in nature, mostly as a result of evolution and
due to basic physical and chemical constraints of polypeptide chains.
Fold recognition methods are useful for protein structure prediction, evolutionary
analysis, metabolic pathways and enzymatic efficiency prediction, molecular docking
and drug design.
Currently there are about 1300 discovered and characterized protein folds in SCOP and
CATH databases. Every newly discovered protein sequence has significant chances to
be classified into one of those folds. Many different approaches have been proposed for
finding the correct fold for a new sequence and it is often useful to include evolutionary
information for query as well as for target proteins.…
Structural genomics is the wide term which describes process of determination of structure representation of information in human genome and at present is limited almost exclusively on proteins. Although in common understanding genetic information means “genes and their encoded protein products”, thousands of human genes produce transcripts which are important in biological point of view but they do not necessarily produce proteins. Furthermore, even though the sequence of the human DNA is known by now, the meaning of the most of the sequences still remains unknown. It is very likely that a large amount of genes has been highly underestimated, mainly because the actual gene finders only work well for large, highly expressed, evolutionary conserved protein-coding genes. Most of those genome elements encode for RNA from which transfer and ribosomal RNAs are the classical examples. But beside these well-known molecules there is a vast unknown world of tiny RNAs that might play a crucial …
ISC has evolved into a high-powered international conference and exhibition that gives its attendees a global perspective on the cutting edge of HPC. As always, our conference program tackles hot HPC topics; this year, for example, we will have a panel session on “Green Computing”, a topic that was almost unknown just two years ago. ISC’s focus on future trends and developments can also be seen in this year’s keynote presentation by Prof. Dr. Satoshi Matsuoka of the Tokyo Institute of Technology, Japan, who will discuss “Everybody Supercomputes in the Next Generation Cyber-Science Infrastructure”. I look forward to seeing you in Dresden.