Self-driven web technologist and cross-platform solutions enthusiast with strong analytic mind. Interest in pattern recognition and integration between web platforms and databases. PhD and Engineering degrees in fields of chemistry / bioinformatics with a strong publication record in peer-reviewed journals. Java, Python & PHP programmer. Keen on rock music and rock climbing
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International Supercomputing Conference, Dresden, Germany
ISC has evolved into a high-powered international conference and exhibition that gives its attendees a global perspective on the cutting edge of HPC. As always, our conference program tackles hot HPC topics; this year, for example, we will have a panel session on “Green Computing”, a topic that was almost unknown just two years ago. ISC’s focus on future trends and developments can also be seen in this year’s keynote presentation by Prof. Dr. Satoshi Matsuoka of the Tokyo Institute of Technology, Japan, who will discuss “Everybody Supercomputes in the Next Generation Cyber-Science Infrastructure”. I look forward to seeing you in Dresden.
The International Supercomputing Conference is the Europe’s premier HPC event. The attendance allows observing trends science and technology of High Performance Computing for whole next year. 2009 edition achieved record numbers of attendees and exhibitors, a level of success even more impressive given the international economic crisis. With its move to Hamburg, ISC’09 reached a significantly higher level of attendance, bringing 1,670 HPC industry leaders. Research labs demonstrated their scientific applications of supercomputing in most recent fields such us GPGPU accelerators, clouds and green computing. Furthermore, this, ISC’09 also welcomed several first-time exhibitors. The exhibition brought countless highlights such as the demo of both the IS5000 40 Gb/s infniband switches and low-latency 10 Gigabit Ethernet. The attendance on ISC’09 allows to anticipate future development of ATLAS system and to present current achievements’ of ToK4nEDA team.
Structural genomics is the wide term which describes process of determination of structure representation of information in human genome and at present is limited almost exclusively on proteins. Although in common understanding genetic information means “genes and their encoded protein products”, thousands of human genes produce transcripts which are important in biological point of view but they do not necessarily produce proteins. Furthermore, even though the sequence of the human DNA is known by now, the meaning of the most of the sequences still remains unknown. It is very likely that a large amount of genes has been highly underestimated, mainly because the actual gene finders only work well for large, highly expressed, evolutionary conserved protein-coding genes. Most of those genome elements encode for RNA from which transfer and ribosomal RNAs are the classical examples. But beside these well-known molecules there is a vast unknown world of tiny RNAs that might play a crucial …
Linear motifs are short segments of multidomain proteins that provide regulatory functions independently of protein tertiary structure. Much of intracellular signalling passes through protein modifications at linear motifs. Many thousands of linear motif instances, most notably phosphorylation sites, have now been reported. Although clearly very abundant, linear motifs are difficult to predict de novo in protein sequences due to the difficulty of obtaining robust statistical assessments. The ELM resource at http://elm.eu.org/ provides an expanding knowledge base, currently covering 146 known motifs, with annotation that includes >1300 experimentally reported instances. ELM is also an exploratory tool for suggesting new candidates of known linear motifs in proteins of interest. Information about protein domains, protein structure and native disorder, cellular and taxonomic contexts is used to reduce or deprecate false positive matches. Results are graphically displayed in a 'Bar…